Thyroid Peroxidase (TPO) Antibody
The Thyroid Peroxidase (TPO) Antibody test provides differential diagnosis of hypothyroidism and thyroiditis.
Should be used in conjunction with antithyroglobulin test, since autoimmune thyroiditis may demonstrate a response to antigens other than thyroid microsomes. To order both antithyroglobulin and antimicrosomal tests, order test number 006684 (Thyroid Antibodies). Other autoimmune disorders such as Sjögren’s syndrome, lupus erythematosus, rheumatoid arthritis, pernicious anemia, and others may be positive for antimicrosomal and antithyroglobulin. Patients with myxedema, granulomatous thyroiditis, nontoxic nodular goiter, and thyroid carcinoma may occasionally produce thyroid antibodies.