The Total Cholesterol test is used to evaluate lipid status and metabolic disorders.
Cholesterol relates to coronary heart disease risk. Since premature mortality from coronary arterial disease is rampant and since cholesterol levels are available as a test which can detect a modifiable risk factor, serum cholesterol remains a critical and genuinely newsworthy topic and an important test. Effective intervention is available when cholesterol studies identify subjects likely to benefit, asymptomatic persons as well as those with recognized coronary disease.
High levels of cholesterol that reflect high levels of HPLs may be caused by an inherited defect in lipoprotein metabolism, by disease of the endocrine system, by liver disease, or by renal disease. Low levels of cholesterol in the plasma may reflect an inherited deficiency of either LDL or HDL, or they may reflect impairment of liver function. Various hormone conditions are also related to cholesterol levels. Increased serum cholesterol in hypothyroid persons shows an increased LDL and decreased HDL. Low cholesterols are found in cases of hyperthyroidism, severe liver disease, pernicious anemia, and with increased estrogens. Pregnancy is accompanied by a moderate increase. Cholesterol is increased in early hepatitis, obstructed bile ducts, primary biliary cirrhosis, nephrotic syndrome, and diabetic meningitis. Finally, through much controversy, it appears that cholesterol is implicated in atherosclerosis and heart disease. Evaluate risk of coronary arterial occlusion, atherosclerosis, myocardial infarction, and complications including the demise of the patient.